Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis

JOURNAL ARTICLE published 11 June 2014 in eLife

Research funded by National Institutes of Health (NIH) (HL20948-37) | Welch Foundation (I-1793) | American Heart Association (AHA) (12SDG12040267) | National Institutes of Health (NIH) (HL20948-37) | Welch Foundation (I-1793) | American Heart Association (AHA) (12SDG12040267)

Authors: Akash Das | Michael S Brown | Donald D Anderson | Joseph L Goldstein | Arun Radhakrishnan

Ketamine induces multiple individually distinct whole-brain functional connectivity signatures

JOURNAL ARTICLE published 17 April 2024 in eLife

Research funded by National Institutes of Health (DP5OD012109-01) | National Institutes of Health (R01MH112746) | National Institutes of Health (5R01MH112189) | National Institutes of Health (5R01MH108590) | National Institute on Alcohol Abuse and Alcoholism (2P50AA012870-11) | National Science Foundation (2015276) | Brain and Behavior Research Foundation (Young Investigator Award) | Simons Foundation Autism Research Initiative (Pilot Award) | Heffter Research Institute (1-190420) | Swiss Neuromatrix Foundation (2016-0111) | Swiss National Science Foundation under the framework of Neuron Cofund (01EW1908) | Usona Institute (2015 - 2056) | National Institutes of Health (1U01MH121766)

Authors: Flora Moujaes | Jie Lisa Ji | Masih Rahmati | Joshua B Burt | Charles Schleifer | Brendan D Adkinson | Aleksandar Savic | Nicole Santamauro | Zailyn Tamayo | Caroline Diehl | Antonija Kolobaric | Morgan Flynn | Nathalie Rieser | Clara Fonteneau | Terry Camarro | Junqian Xu | Youngsun Cho | Grega Repovs | Sarah K Fineberg | Peter T Morgan | Erich Seifritz | Franz X Vollenweider | John H Krystal | John D Murray | Katrin H Preller | Alan Anticevic

A new genus of horse from Pleistocene North America

JOURNAL ARTICLE published 28 November 2017 in eLife

Research funded by National Science Foundation (PLR-1417036) | National Science Foundation (PLR-09090456) | Danish Council for Independent Research Natural Sciences (4002-00152B) | European Research Council (ERC-CoG-2015-681605) | Gordon and Betty Moore Foundation (GBMF3804) | Norges Forskningsråd (250963)

Authors: Peter D Heintzman | Grant D Zazula | Ross DE MacPhee | Eric Scott | James A Cahill | Brianna K McHorse | Joshua D Kapp | Mathias Stiller | Matthew J Wooller | Ludovic Orlando | John Southon | Duane G Froese | Beth Shapiro

Genetic variation in adaptability and pleiotropy in budding yeast

JOURNAL ARTICLE published 17 August 2017 in eLife

Research funded by National Institutes of Health (R01GM102308) | Simons Foundation (376196) | National Science Foundation (PHY 1313638) | Howard Hughes Medical Institute (Investigator) | National Institutes of Health (R01GM104239) | National Science Foundation (Graduate Research Fellowship) | Burroughs Wellcome Fund (Career Award at the Scientific Interface)

Authors: Elizabeth R Jerison | Sergey Kryazhimskiy | James Kameron Mitchell | Joshua S Bloom | Leonid Kruglyak | Michael M Desai

Kinetic modeling predicts a stimulatory role for ribosome collisions at elongation stall sites in bacteria

JOURNAL ARTICLE published 12 May 2017 in eLife

Research funded by National Institute of General Medical Sciences (R35 GM119835) | National Institute of General Medical Sciences (R00 GM107113)

Authors: Michael A Ferrin | Arvind R Subramaniam

Regulation of chromatin architecture by transcription factor binding

JOURNAL ARTICLE published 19 January 2024 in eLife

Research funded by National Institute of General Medical Sciences (R35-GM122562) | National Science Foundation (2151777)

Authors: Stephanie Portillo-Ledesma | Suckwoo Chung | Jill Hoffman | Tamar Schlick

Reprogramming of cardiac phosphoproteome, proteome, and transcriptome confers resilience to chronic adenylyl cyclase-driven stress

JOURNAL ARTICLE published 22 January 2024 in eLife

Authors: Jia-Hua Qu | Khalid Chakir | Kirill V Tarasov | Daniel R Riordon | Maria Grazia Perino | Allwin Jennifa Silvester | Edward G Lakatta

Risk-sensitive learning is a winning strategy for leading an urban invasion

JOURNAL ARTICLE published 2 April 2024 in eLife

Authors: Alexis J Breen | Dominik Deffner

Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

JOURNAL ARTICLE published 4 April 2024 in eLife

Research funded by Eunice Kennedy Shriver National Institute of Child Health and Human Development (1ZIAHD008940) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (1ZIAHD001004)

Authors: Fujun Zhou | Julie M Bocetti | Meizhen Hou | Daoming Qin | Alan G Hinnebusch | Jon R Lorsch

A binding site for phosphoinositides described by multiscale simulations explains their modulation of voltage-gated sodium channels

JOURNAL ARTICLE published 11 March 2024 in eLife

Research funded by Australian Government (Research Training Program Scholarship) | National Computational Infrastructure (NCI HPC-AI Talent Program Scholarship)

Authors: Yiechang Lin | Elaine Tao | James P Champion | Ben Corry

Fine-scale computations for adaptive processing in the human brain

JOURNAL ARTICLE published 10 November 2020 in eLife

Research funded by Biotechnology and Biological Sciences Research Council (H012508) | Biotechnology and Biological Sciences Research Council (BB/P021255/1) | Wellcome Trust (205067/Z/16/Z)

Authors: Elisa Zamboni | Valentin G Kemper | Nuno Reis Goncalves | Ke Jia | Vasilis M Karlaftis | Samuel J Bell | Joseph Giorgio | Reuben Rideaux | Rainer Goebel | Zoe Kourtzi

Mechanistic insights into volatile anesthetic modulation of K2P channels

JOURNAL ARTICLE published 21 December 2020 in eLife

Research funded by Foundation for Anesthesia Education and Research (FAER-182483-2) | National Institute of General Medical Sciences (K08GM132781) | National Institute of General Medical Sciences (P01GM055876)

Authors: Aboubacar Wague | Thomas T Joseph | Kellie A Woll | Weiming Bu | Kiran A Vaidya | Natarajan V Bhanu | Benjamin A Garcia | Crina M Nimigean | Roderic G Eckenhoff | Paul M Riegelhaupt

Human Neocortical Neurosolver (HNN), a new software tool for interpreting the cellular and network origin of human MEG/EEG data

JOURNAL ARTICLE published 22 January 2020 in eLife

Research funded by National Institute of Biomedical Imaging and Bioengineering (BRAIN Award 5-R01-EB022889-02) | National Institute of Biomedical Imaging and Bioengineering (BRAIN Award Supplement R01EB022889-02S1) | National Institute on Deafness and Other Communication Disorders (5-R01DC012947-07) | Army Research Office (W911NF-19-1-0402)

Authors: Samuel A Neymotin | Dylan S Daniels | Blake Caldwell | Robert A McDougal | Nicholas T Carnevale | Mainak Jas | Christopher I Moore | Michael L Hines | Matti Hämäläinen | Stephanie R Jones

The sifting of visual information in the superior colliculus

JOURNAL ARTICLE published 14 April 2020 in eLife

Research funded by Simons Foundation (543015SPI) | National Science Foundation (Graduate Research Fellowship) | National Institutes of Health (1R01NS111477)

Authors: Kyu Hyun Lee | Alvita Tran | Zeynep Turan | Markus Meister

An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution

JOURNAL ARTICLE published 16 February 2021 in eLife

Research funded by Cancer Prevention and Research Institute of Texas (RR170062) | National Science Foundation (1942019) | SDB (Choose Development!)

Authors: Aubrey GA Howard | Phillip A Baker | Rodrigo Ibarra-García-Padilla | Joshua A Moore | Lucia J Rivas | James J Tallman | Eileen W Singleton | Jessa L Westheimer | Julia A Corteguera | Rosa A Uribe

A limbic circuit selectively links active escape to food suppression

JOURNAL ARTICLE published 7 September 2020 in eLife

Research funded by National Institute of Diabetes and Digestive and Kidney Diseases (F32DK107077) | National Institute on Drug Abuse (K99DA048749)

Authors: Estefania P Azevedo | Bowen Tan | Lisa E Pomeranz | Violet Ivan | Robert Fetcho | Marc Schneeberger | Katherine R Doerig | Conor Liston | Jeffrey M Friedman | Sarah A Stern

Complementary codes for odor identity and intensity in olfactory cortex

JOURNAL ARTICLE published 5 April 2017 in eLife

Research funded by National Institutes of Health (DC009839) | National Institutes of Health (DC015525)

Authors: Kevin A Bolding | Kevin M Franks

Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

JOURNAL ARTICLE published 9 April 2024 in eLife

Research funded by Ministry of Science and Higher Education of the Russian Federation (075-15-2019-1789)

Authors: Tatyana O Nakonechnaya | Bruno Moltedo | Ekaterina V Putintseva | Sofya Leyn | Dmitry A Bolotin | Olga V Britanova | Mikhail Shugay | Dmitriy M Chudakov

A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

JOURNAL ARTICLE published 14 December 2020 in eLife

Research funded by National Institute of General Medical Sciences (R35GM124780) | National Institute of Diabetes and Digestive and Kidney Diseases (R01DK110358) | National Human Genome Research Institute (R01HG009299) | Glenn Foundation for Medical Research (Glenn Award) | National Human Genome Research Institute (T32HG008962) | Might family (Bertrand T Might Fellowship) | National Institute of General Medical Sciences (T32GM007464)

Authors: Dana M Talsness | Katie G Owings | Emily Coelho | Gaelle Mercenne | John M Pleinis | Raghavendran Partha | Kevin A Hope | Aamir R Zuberi | Nathan L Clark | Cathleen M Lutz | Aylin R Rodan | Clement Y Chow

TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte–tracheal interactions

JOURNAL ARTICLE published 7 December 2020 in eLife

Research funded by National Institutes of Health (RO1 NS03538) | Oregon Health and Science University (NIH RO1 NS053538)

Authors: Zhiguo Ma | Marc R Freeman