A mobile genetic element increases bacterial host fitness by manipulating development

JOURNAL ARTICLE published 3 March 2021 in eLife

Research funded by National Institute of General Medical Sciences (R01 GM050895) | National Institute of General Medical Sciences (R35 GM122538)

Authors: Joshua M Jones | Ilana Grinberg | Avigdor Eldar | Alan D Grossman

Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila

JOURNAL ARTICLE published 17 December 2018 in eLife

Research funded by Biotechnology and Biological Sciences Research Council (BB/I01179X/1) | Biotechnology and Biological Sciences Research Council (BB/M002934/1) | Biotechnology and Biological Sciences Research Council (BB/I012273/1) | Biotechnology and Biological Sciences Research Council (BB/M002322/1) | Biotechnology and Biological Sciences Research Council (BB/N/014561/1)

Authors: Matthew CW Oswald | Paul S Brooks | Maarten F Zwart | Amrita Mukherjee | Ryan JH West | Carlo NG Giachello | Khomgrit Morarach | Richard A Baines | Sean T Sweeney | Matthias Landgraf

Ketamine induces multiple individually distinct whole-brain functional connectivity signatures

JOURNAL ARTICLE published 17 April 2024 in eLife

Research funded by National Institutes of Health (DP5OD012109-01) | National Institutes of Health (R01MH112746) | National Institutes of Health (5R01MH112189) | National Institutes of Health (5R01MH108590) | National Institute on Alcohol Abuse and Alcoholism (2P50AA012870-11) | National Science Foundation (2015276) | Brain and Behavior Research Foundation (Young Investigator Award) | Simons Foundation Autism Research Initiative (Pilot Award) | Heffter Research Institute (1-190420) | Swiss Neuromatrix Foundation (2016-0111) | Swiss National Science Foundation under the framework of Neuron Cofund (01EW1908) | Usona Institute (2015 - 2056) | National Institutes of Health (1U01MH121766)

Authors: Flora Moujaes | Jie Lisa Ji | Masih Rahmati | Joshua B Burt | Charles Schleifer | Brendan D Adkinson | Aleksandar Savic | Nicole Santamauro | Zailyn Tamayo | Caroline Diehl | Antonija Kolobaric | Morgan Flynn | Nathalie Rieser | Clara Fonteneau | Terry Camarro | Junqian Xu | Youngsun Cho | Grega Repovs | Sarah K Fineberg | Peter T Morgan | Erich Seifritz | Franz X Vollenweider | John H Krystal | John D Murray | Katrin H Preller | Alan Anticevic

Regulation of chromatin architecture by transcription factor binding

JOURNAL ARTICLE published 19 January 2024 in eLife

Research funded by National Institute of General Medical Sciences (R35-GM122562) | National Science Foundation (2151777)

Authors: Stephanie Portillo-Ledesma | Suckwoo Chung | Jill Hoffman | Tamar Schlick

Reprogramming of cardiac phosphoproteome, proteome, and transcriptome confers resilience to chronic adenylyl cyclase-driven stress

JOURNAL ARTICLE published 22 January 2024 in eLife

Authors: Jia-Hua Qu | Khalid Chakir | Kirill V Tarasov | Daniel R Riordon | Maria Grazia Perino | Allwin Jennifa Silvester | Edward G Lakatta

Risk-sensitive learning is a winning strategy for leading an urban invasion

JOURNAL ARTICLE published 2 April 2024 in eLife

Authors: Alexis J Breen | Dominik Deffner

Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

JOURNAL ARTICLE published 4 April 2024 in eLife

Research funded by Eunice Kennedy Shriver National Institute of Child Health and Human Development (1ZIAHD008940) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (1ZIAHD001004)

Authors: Fujun Zhou | Julie M Bocetti | Meizhen Hou | Daoming Qin | Alan G Hinnebusch | Jon R Lorsch

A binding site for phosphoinositides described by multiscale simulations explains their modulation of voltage-gated sodium channels

JOURNAL ARTICLE published 11 March 2024 in eLife

Research funded by Australian Government (Research Training Program Scholarship) | National Computational Infrastructure (NCI HPC-AI Talent Program Scholarship)

Authors: Yiechang Lin | Elaine Tao | James P Champion | Ben Corry

Mechanistic insights into volatile anesthetic modulation of K2P channels

JOURNAL ARTICLE published 21 December 2020 in eLife

Research funded by Foundation for Anesthesia Education and Research (FAER-182483-2) | National Institute of General Medical Sciences (K08GM132781) | National Institute of General Medical Sciences (P01GM055876)

Authors: Aboubacar Wague | Thomas T Joseph | Kellie A Woll | Weiming Bu | Kiran A Vaidya | Natarajan V Bhanu | Benjamin A Garcia | Crina M Nimigean | Roderic G Eckenhoff | Paul M Riegelhaupt

Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

JOURNAL ARTICLE published 9 April 2024 in eLife

Research funded by Ministry of Science and Higher Education of the Russian Federation (075-15-2019-1789)

Authors: Tatyana O Nakonechnaya | Bruno Moltedo | Ekaterina V Putintseva | Sofya Leyn | Dmitry A Bolotin | Olga V Britanova | Mikhail Shugay | Dmitriy M Chudakov

Discovery and characterization of a novel family of prokaryotic nanocompartments involved in sulfur metabolism

JOURNAL ARTICLE published 6 April 2021 in eLife

Research funded by U.S. Department of Energy (Grant DE-SC00016240) | National Science Foundation (GRFP-1106400)

Authors: Robert J Nichols | Benjamin LaFrance | Naiya R Phillips | Devon R Radford | Luke M Oltrogge | Luis E Valentin-Alvarado | Amanda J Bischoff | Eva Nogales | David F Savage

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

JOURNAL ARTICLE published 25 January 2021 in eLife

Research funded by Swiss Cancer Research foundation (KLS-3388-02-2014) | European Research Council (Marie Curie Intra-European Fellowships PIEF-GA-2013-629414) | University of Seville (postdoctoral contract of the V PPIT-US) | Junta de Andalucía (CABIMER)

Authors: Fernando R Balestra | Andrés Domínguez-Calvo | Benita Wolf | Coralie Busso | Alizée Buff | Tessa Averink | Marita Lipsanen-Nyman | Pablo Huertas | Rosa M Ríos | Pierre Gönczy

SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation

JOURNAL ARTICLE published 9 March 2022 in eLife

Research funded by National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR071967) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR076325)

Authors: Leyao Shen | Yilin Yu | Yunji Zhou | Shondra M Pruett-Miller | Guo-Fang Zhang | Courtney M Karner

HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

JOURNAL ARTICLE published 18 May 2021 in eLife

Research funded by NIH Office of the Director (GM58800)

Authors: Heesun Kim | Yue-He Ding | Gangming Zhang | Yong-Hong Yan | Darryl Conte | Meng-Qiu Dong | Craig C Mello

Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels compared to protease inhibitor-based therapy

JOURNAL ARTICLE published 13 August 2021 in eLife

Research funded by ZonMw (09120011910035) | FP7 Health (305522)

Authors: Alexander O Pasternak | Jelmer Vroom | Neeltje A Kootstra | Ferdinand WNM Wit | Marijn de Bruin | Davide De Francesco | Margreet Bakker | Caroline A Sabin | Alan Winston | Jan M Prins | Peter Reiss | Ben Berkhout | P Reiss | FWNM Wit | J Schouten | KW Kooij | RA van Zoest | BC Elsenga | FR Janssen | M Heidenrijk | W Zikkenheiner | M van der Valk | NA Kootstra | T Booiman | AM Harskamp-Holwerda | I Maurer | MM Mangas Ruiz | AF Girigorie | J Villaudy | E Frankin | AO Pasternak | B Berkhout | T van der Kuyl | P Portegies | BA Schmand | GJ Geurtsen | JA ter Stege | M Klein Twennaar | CBLM Majoie | MWA Caan | T Su | K Weijer | PHLT Bisschop | A Kalsbeek | M Wezel | I Visser | HG Ruhé | C Franceschi | P Garagnani | C Pirazzini | M Capri | F Dall'Olio | M Chiricolo | S Salvioli | J Hoeijmakers | J Pothof | M Prins | M Martens | S Moll | J Berkel | M Totté | S Kovalev | M Gisslén | D Fuchs | H Zetterberg | A Winston | J Underwood | L McDonald | M Stott | K Legg | A Lovell | O Erlwein | N Doyle | C Kingsley | DJ Sharp | R Leech | JH Cole | S Zaheri | MMJ Hillebregt | YMC Ruijs | DP Benschop | D Burger | M de Graaff-Teulen | G Guaraldi | A Bürkle | T Sindlinger | M Moreno-Villanueva | A Keller | C Sabin | D de Francesco | C Libert | S Dewaele | The Co-morBidity in Relation to Aids (COBRA) Collaboration

Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice

JOURNAL ARTICLE published 23 December 2019 in eLife

Research funded by National Institute of Neurological Disorders and Stroke (NS105470) | National Institute of Neurological Disorders and Stroke (NS089716)

Authors: Samantha Washburn | Rachel Fremont | Maria Camila Moreno-Escobar | Chantal Angueyra | Kamran Khodakhah

Global cellular response to chemical perturbation of PLK4 activity and abnormal centrosome number

JOURNAL ARTICLE published 27 June 2022 in eLife

Research funded by Canadian Institutes of Health Research (CIHR FDN 167279)

Authors: Johnny M Tkach | Reuben Philip | Amit Sharma | Jonathan Strecker | Daniel Durocher | Laurence Pelletier

MorphoFeatures for unsupervised exploration of cell types, tissues, and organs in volume electron microscopy

JOURNAL ARTICLE published 16 February 2023 in eLife

Research funded by European Research Council (788921)

Authors: Valentyna Zinchenko | Johannes Hugger | Virginie Uhlmann | Detlev Arendt | Anna Kreshuk

TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls

JOURNAL ARTICLE published 14 September 2016 in eLife

Authors: Matyáš Fendrych | Jeffrey Leung | Jiří Friml

SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

JOURNAL ARTICLE published 16 March 2022 in eLife

Authors: Michela Zaffagni | Jenna M Harris | Ines L Patop | Nagarjuna Reddy Pamudurti | Sinead Nguyen | Sebastian Kadener