Single cell preparations of Mycobacterium tuberculosis damage the mycobacterial envelope and disrupt macrophage interactions

JOURNAL ARTICLE published 28 February 2023 in eLife

Research funded by NIAID/NIH (R01 AI087682) | NIAID/NIH (R01 AI30454) | National Cancer Institute (NCI)-Innovative Molecular Analysis Technologies (R21CA236652) | National Science Foundation (CBET-1900277) | NIH/NHLBI (T32 HL007317-37)

Authors: Ekansh Mittal | Andrew T Roth | Anushree Seth | Srikanth Singamaneni | Wandy Beatty | Jennifer A Philips

Identification of neural progenitor cells and their progeny reveals long distance migration in the developing octopus brain

JOURNAL ARTICLE published 24 August 2021 in eLife

Research funded by Fonds Wetenschappelijk Onderzoek (SB/1S19517N) | Fonds Wetenschappelijk Onderzoek (SB/11D4120N) | KU Leuven (ID-N/20/007) | KU Leuven (IOFm/17/014)

Authors: Astrid Deryckere | Ruth Styfhals | Ali Murat Elagoz | Gregory E Maes | Eve Seuntjens

Filopodia powered by class x myosin promote fusion of mammalian myoblasts

JOURNAL ARTICLE published 14 September 2021 in eLife

Research funded by National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01-AR075637) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (U54-AR-052646) | Fondation Leducq (13CVD04) | Muscular Dystrophy Association (MDA549004) | National Institute of General Medical Sciences (R01-GM134531) | National Cancer Institute (T32CA009156)

Authors: David W Hammers | Cora C Hart | Michael K Matheny | Ernest G Heimsath | Young il Lee | John A Hammer | Richard E Cheney | H Lee Sweeney

Acetylcholine acts on songbird premotor circuitry to invigorate vocal output

JOURNAL ARTICLE published 19 May 2020 in eLife

Authors: Paul I Jaffe | Michael S Brainard

GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis

JOURNAL ARTICLE published 13 November 2020 in eLife

Research funded by National Institute of Neurological Disorders and Stroke (NS094637)

Authors: Markus Terrey | Scott I Adamson | Alana L Gibson | Tianda Deng | Ryuta Ishimura | Jeffrey H Chuang | Susan L Ackerman

In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stress

JOURNAL ARTICLE published 5 January 2018 in eLife

Research funded by Cancer Research UK (C33269/A20752) | Cancer Research UK (C33269/A23215)

Authors: Megan C Kopp | Piotr R Nowak | Natacha Larburu | Christopher J Adams | Maruf MU Ali

The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family

JOURNAL ARTICLE published 27 April 2020 in eLife

Research funded by Science Foundation Ireland (13/IA/1910) | European Research Council (789341)

Authors: Aisling Y Coughlan | Lisa Lombardi | Stephanie Braun-Galleani | Alexandre AR Martos | Virginie Galeote | Frédéric Bigey | Sylvie Dequin | Kevin P Byrne | Kenneth H Wolfe

Functional visualization of NK cell-mediated killing of metastatic single tumor cells

JOURNAL ARTICLE published 3 February 2022 in eLife

Research funded by Japan Society for the Promotion of Science (18K15317) | Japan Society for the Promotion of Science (15H05949) | Japan Society for the Promotion of Science (19H00993) | Japan Agency for Medical Research and Development (19gm5010003h0003) | Core Research for Evolutional Science and Technology (JPMJCR1654)

Authors: Hiroshi Ichise | Shoko Tsukamoto | Tsuyoshi Hirashima | Yoshinobu Konishi | Choji Oki | Shinya Tsukiji | Satoshi Iwano | Atsushi Miyawaki | Kenta Sumiyama | Kenta Terai | Michiyuki Matsuda

Pupil diameter encodes the idiosyncratic, cognitive complexity of belief updating

JOURNAL ARTICLE published 18 May 2020 in eLife

Research funded by National Science Foundation (NSF-NCS 1533623) | National Institute of Biomedical Imaging and Bioengineering (R01 EB026945) | National Institute of Mental Health (F32 MH117924)

Authors: Alexandre LS Filipowicz | Christopher M Glaze | Joseph W Kable | Joshua I Gold

Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket

JOURNAL ARTICLE published 10 February 2017 in eLife

Research funded by National Eye Institute (EY06837) | National Eye Institute (EY001157) | National Natural Science Foundation of China (31471053) | Antonio Champalimaud Foundation, Portugal (Antonio Champalimaud Vision Award) | Howard Hughes Medical Institute (International Student Research Fellowships)

Authors: Wendy Wing Sze Yue | Rikard Frederiksen | Xiaozhi Ren | Dong-Gen Luo | Takahiro Yamashita | Yoshinori Shichida | M Carter Cornwall | King-Wai Yau

Testosterone pulses paired with a location induce a place preference to the nest of a monogamous mouse under field conditions

JOURNAL ARTICLE published 30 March 2022 in eLife

Research funded by National Science Foundation (1355163) | Sigma Xi (Spring 2018)

Authors: Radmila Petric | Matina Kalcounis-Rueppell | Catherine A Marler

Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development

JOURNAL ARTICLE published 19 July 2018 in eLife

Research funded by National Research Foundation Singapore (NRF2011NRF-NRFF001-042) | National Institutes of Health (R01-GM083300) | Ministry of Education - Singapore (MOE2014-T2-2-039) | National University of Singapore (R-154-000-536-133) | National Institutes of Health (R01-NS083833) | National University of Singapore (R-154-000-562-112) | National University of Singapore (R-154-000-582-651)

Authors: Li Zhou | Mandy Yu Theng Lim | Prameet Kaur | Abil Saj | Diane Bortolamiol-Becet | Vikneswaran Gopal | Nicholas Tolwinski | Greg Tucker-Kellogg | Katsutomo Okamura

Scavenger receptor endocytosis controls apical membrane morphogenesis in the Drosophila airways

JOURNAL ARTICLE published 14 September 2023 in eLife

Research funded by Magnus Bergvalls Stiftelse (2021-04453) | Deutsche Forschungsgemeinschaft (KFO309)

Authors: Ana Sofia Pinheiro | Vasilios Tsarouhas | Kirsten André Senti | Badrul Arefin | Christos Samakovlis

A Toll-receptor map underlies structural brain plasticity

JOURNAL ARTICLE published 18 February 2020 in eLife

Research funded by Biotechnology and Biological Sciences Research Council (BB/P004997/1) | Biotechnology and Biological Sciences Research Council (BB/R017034/1) | H2020 Marie Skłodowska-Curie Actions (NPN)

Authors: Guiyi Li | Manuel G Forero | Jill S Wentzell | Ilgim Durmus | Reinhard Wolf | Niki C Anthoney | Mieczyslaw Parker | Ruiying Jiang | Jacob Hasenauer | Nicholas James Strausfeld | Martin Heisenberg | Alicia Hidalgo

Single-cell analysis of the aged ovarian immune system reveals a shift towards adaptive immunity and attenuated cell function

JOURNAL ARTICLE published 25 April 2023 in eLife

Research funded by Israel Science Foundation (1619/20)

Authors: Tal Ben Yaakov | Tanya Wasserman | Eliel Aknin | Yonatan Savir

The molecular architecture of engulfment during Bacillus subtilis sporulation

JOURNAL ARTICLE published 8 July 2019 in eLife

Research funded by National Institutes of Health (National Institute of Health's Director's New Innovator Award (1DP2GM123494)) | National Institutes of Health (RO1-GM057045)

Authors: Kanika Khanna | Javier Lopez-Garrido | Ziyi Zhao | Reika Watanabe | Yuan Yuan | Joseph Sugie | Kit Pogliano | Elizabeth Villa

Molecular mechanisms that stabilize short term synaptic plasticity during presynaptic homeostatic plasticity

JOURNAL ARTICLE published 13 November 2018 in eLife

Research funded by National Institute of Neurological Disorders and Stroke (R35NS097212)

Authors: Jennifer M Ortega | Özgür Genç | Graeme W Davis

A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability

JOURNAL ARTICLE published 22 May 2018 in eLife

Research funded by Agency for Science, Technology and Research (GODAFIT Strategic Positioning Fund)

Authors: Poh Hui Chia | Franklin Lei Zhong | Shinsuke Niwa | Carine Bonnard | Kagistia Hana Utami | Ruizhu Zeng | Hane Lee | Ascia Eskin | Stanley F Nelson | William H Xie | Samah Al-Tawalbeh | Mohammad El-Khateeb | Mohammad Shboul | Mahmoud A Pouladi | Mohammed Al-Raqad | Bruno Reversade

Lotka-Volterra pairwise modeling fails to capture diverse pairwise microbial interactions

JOURNAL ARTICLE published 28 March 2017 in eLife

Authors: Babak Momeni | Li Xie | Wenying Shou

Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis

JOURNAL ARTICLE published 21 February 2023 in eLife

Research funded by Japan Society for the Promotion of Science (JP19H03449) | Japan Society for the Promotion of Science (JP20K06535) | Japan Society for the Promotion of Science (JP20K15742)

Authors: Kunli Zhao | Kohichi Matsunaga | Kouichi Mizuno | Hao Wang | Katsuhide Okunishi | Tetsuro Izumi