Fine-scale computations for adaptive processing in the human brain

JOURNAL ARTICLE published 10 November 2020 in eLife

Research funded by Biotechnology and Biological Sciences Research Council (H012508) | Biotechnology and Biological Sciences Research Council (BB/P021255/1) | Wellcome Trust (205067/Z/16/Z)

Authors: Elisa Zamboni | Valentin G Kemper | Nuno Reis Goncalves | Ke Jia | Vasilis M Karlaftis | Samuel J Bell | Joseph Giorgio | Reuben Rideaux | Rainer Goebel | Zoe Kourtzi

Mechanistic insights into volatile anesthetic modulation of K2P channels

JOURNAL ARTICLE published 21 December 2020 in eLife

Research funded by Foundation for Anesthesia Education and Research (FAER-182483-2) | National Institute of General Medical Sciences (K08GM132781) | National Institute of General Medical Sciences (P01GM055876)

Authors: Aboubacar Wague | Thomas T Joseph | Kellie A Woll | Weiming Bu | Kiran A Vaidya | Natarajan V Bhanu | Benjamin A Garcia | Crina M Nimigean | Roderic G Eckenhoff | Paul M Riegelhaupt

Human Neocortical Neurosolver (HNN), a new software tool for interpreting the cellular and network origin of human MEG/EEG data

JOURNAL ARTICLE published 22 January 2020 in eLife

Research funded by National Institute of Biomedical Imaging and Bioengineering (BRAIN Award 5-R01-EB022889-02) | National Institute of Biomedical Imaging and Bioengineering (BRAIN Award Supplement R01EB022889-02S1) | National Institute on Deafness and Other Communication Disorders (5-R01DC012947-07) | Army Research Office (W911NF-19-1-0402)

Authors: Samuel A Neymotin | Dylan S Daniels | Blake Caldwell | Robert A McDougal | Nicholas T Carnevale | Mainak Jas | Christopher I Moore | Michael L Hines | Matti Hämäläinen | Stephanie R Jones

An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution

JOURNAL ARTICLE published 16 February 2021 in eLife

Research funded by Cancer Prevention and Research Institute of Texas (RR170062) | National Science Foundation (1942019) | SDB (Choose Development!)

Authors: Aubrey GA Howard | Phillip A Baker | Rodrigo Ibarra-García-Padilla | Joshua A Moore | Lucia J Rivas | James J Tallman | Eileen W Singleton | Jessa L Westheimer | Julia A Corteguera | Rosa A Uribe

Complementary codes for odor identity and intensity in olfactory cortex

JOURNAL ARTICLE published 5 April 2017 in eLife

Research funded by National Institutes of Health (DC009839) | National Institutes of Health (DC015525)

Authors: Kevin A Bolding | Kevin M Franks

Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

JOURNAL ARTICLE published 9 April 2024 in eLife

Research funded by Ministry of Science and Higher Education of the Russian Federation (075-15-2019-1789)

Authors: Tatyana O Nakonechnaya | Bruno Moltedo | Ekaterina V Putintseva | Sofya Leyn | Dmitry A Bolotin | Olga V Britanova | Mikhail Shugay | Dmitriy M Chudakov

A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

JOURNAL ARTICLE published 14 December 2020 in eLife

Research funded by National Institute of General Medical Sciences (R35GM124780) | National Institute of Diabetes and Digestive and Kidney Diseases (R01DK110358) | National Human Genome Research Institute (R01HG009299) | Glenn Foundation for Medical Research (Glenn Award) | National Human Genome Research Institute (T32HG008962) | Might family (Bertrand T Might Fellowship) | National Institute of General Medical Sciences (T32GM007464)

Authors: Dana M Talsness | Katie G Owings | Emily Coelho | Gaelle Mercenne | John M Pleinis | Raghavendran Partha | Kevin A Hope | Aamir R Zuberi | Nathan L Clark | Cathleen M Lutz | Aylin R Rodan | Clement Y Chow

TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte–tracheal interactions

JOURNAL ARTICLE published 7 December 2020 in eLife

Research funded by National Institutes of Health (RO1 NS03538) | Oregon Health and Science University (NIH RO1 NS053538)

Authors: Zhiguo Ma | Marc R Freeman

Synthetic hormone-responsive transcription factors can monitor and re-program plant development

JOURNAL ARTICLE published 1 May 2018 in eLife

Research funded by National Science Foundation (MCB-1411949) | National Institutes of Health (R01-GM107084) | Howard Hughes Medical Institute (Faculty Scholars Program)

Authors: Arjun Khakhar | Alexander R Leydon | Andrew C Lemmex | Eric Klavins | Jennifer L Nemhauser

Discovery and characterization of a novel family of prokaryotic nanocompartments involved in sulfur metabolism

JOURNAL ARTICLE published 6 April 2021 in eLife

Research funded by U.S. Department of Energy (Grant DE-SC00016240) | National Science Foundation (GRFP-1106400)

Authors: Robert J Nichols | Benjamin LaFrance | Naiya R Phillips | Devon R Radford | Luke M Oltrogge | Luis E Valentin-Alvarado | Amanda J Bischoff | Eva Nogales | David F Savage

Enteroendocrine cell types that drive food reward and aversion

JOURNAL ARTICLE published 1 August 2022 in eLife

Research funded by National Institutes of Health (R01-DK106399) | National Institutes of Health (RF1-NS116626) | Howard Hughes Medical Institute (Investigator)

Authors: Ling Bai | Nilla Sivakumar | Shenliang Yu | Sheyda Mesgarzadeh | Tom Ding | Truong Ly | Timothy V Corpuz | James CR Grove | Brooke C Jarvie | Zachary A Knight

Combined transcriptome and proteome profiling reveals specific molecular brain signatures for sex, maturation and circalunar clock phase

JOURNAL ARTICLE published 15 February 2019 in eLife

Research funded by European Research Council ((FP7/2007-2013)/ERC Grant Agreement 260304) | European Research Council ((FP7/2007-2013)/ERC Grant Agreement 337011) | University of Vienna (Research Platform Rhythms of Life) | Austrian Science Fund (#AY0041321) | Austrian Science Fund (#P28970) | Austrian Science Fund (#I2972) | Austrian Science Fund (#M1478) | Vienna International PostDoctoral Program for Molecular Life Sciences (#GM100402) | European Molecular Biology Organization (YIP #2893)

Authors: Sven Schenk | Stephanie C Bannister | Fritz J Sedlazeck | Dorothea Anrather | Bui Quang Minh | Andrea Bileck | Markus Hartl | Arndt von Haeseler | Christopher Gerner | Florian Raible | Kristin Tessmar-Raible

Testosterone pulses paired with a location induce a place preference to the nest of a monogamous mouse under field conditions

JOURNAL ARTICLE published 30 March 2022 in eLife

Research funded by National Science Foundation (1355163) | Sigma Xi (Spring 2018)

Authors: Radmila Petric | Matina Kalcounis-Rueppell | Catherine A Marler

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

JOURNAL ARTICLE published 25 January 2021 in eLife

Research funded by Swiss Cancer Research foundation (KLS-3388-02-2014) | European Research Council (Marie Curie Intra-European Fellowships PIEF-GA-2013-629414) | University of Seville (postdoctoral contract of the V PPIT-US) | Junta de Andalucía (CABIMER)

Authors: Fernando R Balestra | Andrés Domínguez-Calvo | Benita Wolf | Coralie Busso | Alizée Buff | Tessa Averink | Marita Lipsanen-Nyman | Pablo Huertas | Rosa M Ríos | Pierre Gönczy

Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments

JOURNAL ARTICLE published 16 August 2016 in eLife

Research funded by Wellcome Trust (098375/Z/12/Z) | Biotechnology and Biological Sciences Research Council (BB/N005570/1) | Royal Society (RG130585)

Authors: Didi He | Sam Hughes | Sally Vanden-Hehir | Atanas Georgiev | Kirsten Altenbach | Emma Tarrant | C Logan Mackay | Kevin J Waldron | David J Clarke | Jon Marles-Wright

SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation

JOURNAL ARTICLE published 9 March 2022 in eLife

Research funded by National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR071967) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR076325)

Authors: Leyao Shen | Yilin Yu | Yunji Zhou | Shondra M Pruett-Miller | Guo-Fang Zhang | Courtney M Karner

HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

JOURNAL ARTICLE published 18 May 2021 in eLife

Research funded by NIH Office of the Director (GM58800)

Authors: Heesun Kim | Yue-He Ding | Gangming Zhang | Yong-Hong Yan | Darryl Conte | Meng-Qiu Dong | Craig C Mello

Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels compared to protease inhibitor-based therapy

JOURNAL ARTICLE published 13 August 2021 in eLife

Research funded by ZonMw (09120011910035) | FP7 Health (305522)

Authors: Alexander O Pasternak | Jelmer Vroom | Neeltje A Kootstra | Ferdinand WNM Wit | Marijn de Bruin | Davide De Francesco | Margreet Bakker | Caroline A Sabin | Alan Winston | Jan M Prins | Peter Reiss | Ben Berkhout | P Reiss | FWNM Wit | J Schouten | KW Kooij | RA van Zoest | BC Elsenga | FR Janssen | M Heidenrijk | W Zikkenheiner | M van der Valk | NA Kootstra | T Booiman | AM Harskamp-Holwerda | I Maurer | MM Mangas Ruiz | AF Girigorie | J Villaudy | E Frankin | AO Pasternak | B Berkhout | T van der Kuyl | P Portegies | BA Schmand | GJ Geurtsen | JA ter Stege | M Klein Twennaar | CBLM Majoie | MWA Caan | T Su | K Weijer | PHLT Bisschop | A Kalsbeek | M Wezel | I Visser | HG Ruhé | C Franceschi | P Garagnani | C Pirazzini | M Capri | F Dall'Olio | M Chiricolo | S Salvioli | J Hoeijmakers | J Pothof | M Prins | M Martens | S Moll | J Berkel | M Totté | S Kovalev | M Gisslén | D Fuchs | H Zetterberg | A Winston | J Underwood | L McDonald | M Stott | K Legg | A Lovell | O Erlwein | N Doyle | C Kingsley | DJ Sharp | R Leech | JH Cole | S Zaheri | MMJ Hillebregt | YMC Ruijs | DP Benschop | D Burger | M de Graaff-Teulen | G Guaraldi | A Bürkle | T Sindlinger | M Moreno-Villanueva | A Keller | C Sabin | D de Francesco | C Libert | S Dewaele | The Co-morBidity in Relation to Aids (COBRA) Collaboration

Transient inhibition and long-term facilitation of locomotion by phasic optogenetic activation of serotonin neurons

JOURNAL ARTICLE published 14 February 2017 in eLife

Research funded by Fundação para a Ciência e Tecnologia (SFRH / BD / 33277 / 2007) | Human Frontier Science Program (LT000881/2011L) | Fundação para a Ciência e Tecnologia (SFRH/BD/51210/2010) | Howard Hughes Medical Institute (International Early Career Scientist) | European Research Council (Starting Investigator Grant 640093) | European Research Council (Advanced Investigator Grant 250334) | European Research Council (Advanced Investigator Grant 671251)

Authors: Patrícia A Correia | Eran Lottem | Dhruba Banerjee | Ana S Machado | Megan R Carey | Zachary F Mainen

Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice

JOURNAL ARTICLE published 23 December 2019 in eLife

Research funded by National Institute of Neurological Disorders and Stroke (NS105470) | National Institute of Neurological Disorders and Stroke (NS089716)

Authors: Samantha Washburn | Rachel Fremont | Maria Camila Moreno-Escobar | Chantal Angueyra | Kamran Khodakhah