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COVID-19, microangiopathy, hemostatic activation, and complement JOURNAL ARTICLE published 22 June 2020 in Journal of Clinical Investigation |
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Assuring long-term safety of highly effective gene-modulating therapeutics for rare diseases JOURNAL ARTICLE published 2 August 2021 in Journal of Clinical Investigation |
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Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection JOURNAL ARTICLE published 1 November 2023 in Journal of Clinical Investigation Research funded by NIH GDDTP (T32 HD007009) | American Heart Association (20PRE35210946) | NIH (T32-AI007090) | American Heart Association (13PRE14550022) | American Heart Association (15PRE22180007) | NIH CPBTC (T32 HL07237) | Howard Hughes Medical Institute (Med-into-Grad training program,56006772) | Stamps Family Charitable Foundation (Undergraduate fellowship) | NIAID (P01AI-97113) |
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Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation JOURNAL ARTICLE published 9 January 2017 in Journal of Clinical Investigation |
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A sobering addition to the literature on COVID-19 and the brain JOURNAL ARTICLE published 15 April 2021 in Journal of Clinical Investigation |
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Type I interferon signature and cycling lymphocytes in macrophage activation syndrome JOURNAL ARTICLE published 15 November 2023 in Journal of Clinical Investigation Research funded by National Institute of Arthritis and Musculoskeletal and Skin Diseases (P30-AR070253) | Charles H. Hood Foundation (Child Health Research Award) | Arthritis National Research Foundation (All Arthritis Grant) | Rheumatology Research Foundation (K Supplement Award) |
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HIV-specific CAR T cells return to the clinic JOURNAL ARTICLE published 1 October 2021 in Journal of Clinical Investigation |
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Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression JOURNAL ARTICLE published 23 October 2017 in Journal of Clinical Investigation Research funded by NIH (DK095039,HL119872,HL128158,HL115128,HL099997),U54 CA163167) |
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Nuclear receptors: emerging drug targets for parasitic diseases JOURNAL ARTICLE published 6 February 2017 in Journal of Clinical Investigation |
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Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer JOURNAL ARTICLE published 17 January 2023 in Journal of Clinical Investigation Research funded by National Center Institute (5R01CA152301,P50CA70907,P30 CA008748,P01 CA129243) | CPRIT (RP190107,RP180805) |
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Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development JOURNAL ARTICLE published 9 September 2019 in Journal of Clinical Investigation Research funded by NIH (GM067113,CA068377,) |
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How elite controllers and posttreatment controllers inform our search for an HIV-1 cure JOURNAL ARTICLE published 1 June 2021 in Journal of Clinical Investigation |
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Antibiotic treatment–induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia JOURNAL ARTICLE published 1 August 2018 in Journal of Clinical Investigation Research funded by Deutsche Forschungsgemeinschaft (SFB-TR84) | Deutsche Forschungsgemeinschaft (SPP1656) | Russian Science Foundation (17-74-20059) | Swiss National Science Foundation (31003A_176256) |
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Histone deficiency and accelerated replication stress in T cell aging JOURNAL ARTICLE published 1 June 2021 in Journal of Clinical Investigation Research funded by National Institutes of Health (R01 AR042527,R01 HL117913,R01 AI108906,R01 HL142068,P01 HL129941,R01 AI108891,R01 AG045779,U19 AI057266,R01 AI129191,contract Nr. 75N9301900065) |
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Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis JOURNAL ARTICLE published 21 November 2016 in Journal of Clinical Investigation |
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SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers JOURNAL ARTICLE published 1 June 2022 in Journal of Clinical Investigation |
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Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa JOURNAL ARTICLE published 8 June 2020 in Journal of Clinical Investigation Research funded by Société Française de Dermatologie et de Pathologie Sexuellement Transmissible (R16025JJ) | ANR (ANR-10-LABX-77-01) |
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Sestrin modulator NV-5138 produces rapid antidepressant effects via direct mTORC1 activation JOURNAL ARTICLE published 20 May 2019 in Journal of Clinical Investigation Research funded by NIMH, Navitor Pharmaceuticals Inc. (MH093897,MH105910) |
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αv Integrins regulate germinal center B cell responses through noncanonical autophagy JOURNAL ARTICLE published 31 August 2018 in Journal of Clinical Investigation Research funded by NIH NIAID (RO1DK093695) |
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An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP JOURNAL ARTICLE published 1 February 2022 in Journal of Clinical Investigation Research funded by National Natural Science Foundation of China (81872435) | National Youth Talent Support Program of China (W03070060) | “Tou Yan” Action of Heilongjiang province (2019-15) | National Natural Science Foundation of China (82003030) | National Natural Science Foundation of China (U20A20339) | Natural Science Foundation of Heilongjiang Province (ZD2020H001) | Natural Science Foundation of Heilongjiang Province (JQ2019H003) | HMU Marshal Initiative Funding (HMUMIF-21001) | HMU Marshal Initiative Funding (HMUMIF-21004) |