Type I collagen–targeted PET probe for pulmonary fibrosis detection and staging in preclinical models

JOURNAL ARTICLE published 5 April 2017 in Science Translational Medicine

Research funded by U.S. Department of Energy (award296945) | National Heart, Lung, and Blood Institute (award296946) | NIH Office of the Director (award296947) | National Center for Research Resources (award296948)

Authors: Pauline Désogère | Luis F. Tapias | Lida P. Hariri | Nicholas J. Rotile | Tyson A. Rietz | Clemens K. Probst | Francesco Blasi | Helen Day | Mari Mino-Kenudson | Paul Weinreb | Shelia M. Violette | Bryan C. Fuchs | Andrew M. Tager | Michael Lanuti | Peter Caravan

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice

JOURNAL ARTICLE published 18 May 2016 in Science Translational Medicine

Research funded by NIH (R01-HL069929,R01-AI100288,R01-AI080455,R01-AI101406,R00-CA176376,R01-HL124112) | NCI (P30-CA008748) | NIH Cancer Center Support (P30 CA008748-48)

Authors: Yusuke Shono | Melissa D. Docampo | Jonathan U. Peled | Suelen M. Perobelli | Enrico Velardi | Jennifer J. Tsai | Ann E. Slingerland | Odette M. Smith | Lauren F. Young | Jyotsna Gupta | Sophia R. Lieberman | Hillary V. Jay | Katya F. Ahr | Kori A. Porosnicu Rodriguez | Ke Xu | Marco Calarfiore | Hendrik Poeck | Silvia Caballero | Sean M. Devlin | Franck Rapaport | Jarrod A. Dudakov | Alan M. Hanash | Boglarka Gyurkocza | George F. Murphy | Camilla Gomes | Chen Liu | Eli L. Moss | Shannon B. Falconer | Ami S. Bhatt | Ying Taur | Eric G. Pamer | Marcel R. M. van den Brink | Robert R. Jenq

The Road We Must Take: Multidisciplinary Team Science

JOURNAL ARTICLE published 10 March 2010 in Science Translational Medicine

Authors: Mary L. Disis | John T. Slattery

Bionic Limbs: Clinical Reality and Academic Promises

JOURNAL ARTICLE published 8 October 2014 in Science Translational Medicine

Authors: Dario Farina | Oskar Aszmann

Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting

JOURNAL ARTICLE published 15 June 2022 in Science Translational Medicine

Authors: Mithila Sawant | Kiran Mahajan | Arun Renganathan | Cody Weimholt | Jingqin Luo | Vandna Kukshal | Joseph M. Jez | Myung Sik Jeon | Bo Zhang | Tiandao Li | Bin Fang | Yunting Luo | Nicholas J. Lawrence | Harshani R. Lawrence | Felix Y. Feng | Nupam P. Mahajan

Postnatal Soluble FGFR3 Therapy Rescues Achondroplasia Symptoms and Restores Bone Growth in Mice

JOURNAL ARTICLE published 18 September 2013 in Science Translational Medicine

Authors: Stéphanie Garcia | Béatrice Dirat | Thomas Tognacci | Nathalie Rochet | Xavier Mouska | Stéphanie Bonnafous | Stéphanie Patouraux | Albert Tran | Philippe Gual | Yannick Le Marchand-Brustel | Isabelle Gennero | Elvire Gouze

Modulation of HCV replication after combination antiretroviral therapy in HCV/HIV co-infected patients

JOURNAL ARTICLE published 23 July 2014 in Science Translational Medicine

Authors: Kenneth E. Sherman | Jeremie Guedj | Mohamed Tarek Shata | Jason T. Blackard | Susan D. Rouster | Mario Castro | Judith Feinberg | Richard K. Sterling | Zachary Goodman | Bruce J. Aronow | Alan S. Perelson

Identification of a plant isoflavonoid that causes biliary atresia

JOURNAL ARTICLE published 6 May 2015 in Science Translational Medicine

Research funded by NIH (R01DK092111) | Wellcome Trust (98051) | Kidney Center for Molecular Studies in Digestive and Liver Diseases (P30DK050306)

Authors: Kristin Lorent | Weilong Gong | Kyung A. Koo | Orith Waisbourd-Zinman | Sara Karjoo | Xiao Zhao | Ian Sealy | Ross N. Kettleborough | Derek L. Stemple | Peter A. Windsor | Stephen J. Whittaker | John R. Porter | Rebecca G. Wells | Michael Pack

Type 2–polarized memory B cells hold allergen-specific IgE memory

JOURNAL ARTICLE published 7 February 2024 in Science Translational Medicine

Authors: Joshua F. E. Koenig | Niels Peter H. Knudsen | Allyssa Phelps | Kelly Bruton | Ilka Hoof | Gitte Lund | Danielle Della Libera | Anders Lund | Lars Harder Christensen | David R. Glass | Tina D. Walker | Allison Fang | Susan Waserman | Manel Jordana | Peter S. Andersen

Resiliency and Vulnerability in the HER2-HER3 Tumorigenic Driver

JOURNAL ARTICLE published 27 January 2010 in Science Translational Medicine

Authors: Dhara N. Amin | Natalia Sergina | Deepika Ahuja | Martin McMahon | Jimmy A. Blair | Donghui Wang | Byron Hann | Kevin M. Koch | Kevan M. Shokat | Mark M. Moasser

Dissolving microneedle vaccination—No magic needled

JOURNAL ARTICLE published 26 September 2018 in Science Translational Medicine

Authors: Sam H. Au

HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase

JOURNAL ARTICLE published 12 July 2017 in Science Translational Medicine

Research funded by National Institutes of Health (award310436,R01CA068490) | National Institutes of Health (award310437,P50CA101942)

Authors: Abhishek A. Chakraborty | Eijiro Nakamura | Jun Qi | Amanda Creech | Jacob D. Jaffe | Joshiawa Paulk | Jesse S. Novak | Kshithija Nagulapalli | Samuel K. McBrayer | Glenn S. Cowley | Javier Pineda | Jiaxi Song | Yaoyu E. Wang | Steven A. Carr | David E. Root | Sabina Signoretti | James E. Bradner | William G. Kaelin

dbGaP Data Access Requests: A Call for Greater Transparency

JOURNAL ARTICLE published 14 December 2011 in Science Translational Medicine

Authors: Lorelei Walker | Helene Starks | Kathleen M. West | Stephanie M. Fullerton

The long-acting integrase inhibitor GSK744 protects macaques from repeated intravaginal SHIV challenge

JOURNAL ARTICLE published 14 January 2015 in Science Translational Medicine

Authors: Jessica Radzio | William Spreen | Yun Lan Yueh | James Mitchell | Leecresia Jenkins | J. Gerardo García-Lerma | Walid Heneine

Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria

JOURNAL ARTICLE published 19 September 2018 in Science Translational Medicine

Research funded by MINECO (CTQ2015-68756-R)

Authors: Pedro Urquiza | Ana Laín | Arantza Sanz-Parra | Jorge Moreno | Ganeko Bernardo-Seisdedos | Pierre Dubus | Esperanza González | Virginia Gutiérrez-de-Juan | Sandra García | Hasier Eraña | Itxaso San Juan | Iratxe Macías | Fredj Ben Bdira | Paula Pluta | Gabriel Ortega | Julen Oyarzábal | Rosario González-Muñiz | Juan Rodríguez-Cuesta | Juan Anguita | Emilio Díez | Jean-Marc Blouin | Hubert de Verneuil | José M. Mato | Emmanuel Richard | Juan M. Falcón-Pérez | Joaquín Castilla | Oscar Millet

Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non–small cell lung cancer

JOURNAL ARTICLE published 16 March 2022 in Science Translational Medicine

Authors: Erik Wennerberg | Sumit Mukherjee | Sheila Spada | Clarey Hung | Christopher J. Agrusa | Chuang Chen | Amanda Valeta-Magara | Nils-Petter Rudqvist | Samantha J. Van Nest | Mohamed K. Kamel | Abu Nasar | Navneet Narula | Vivek Mittal | Geoffrey J. Markowitz | Xi Kathy Zhou | Prasad S. Adusumilli | Alain C. Borczuk | Thomas E. White | Abdul G. Khan | Paul J. Balderes | Ivo C. Lorenz | Nasser Altorki | Sandra Demaria | Timothy E. McGraw | Brendon M. Stiles

Agonist-antagonist myoneural interface amputation preserves proprioceptive sensorimotor neurophysiology in lower limbs

JOURNAL ARTICLE published 9 December 2020 in Science Translational Medicine

Authors: Shriya S. Srinivasan | Greta Tuckute | Jasmine Zou | Samantha Gutierrez-Arango | Hyungeun Song | Robert L. Barry | Hugh M. Herr

The SGLT2 inhibitor dapagliflozin improves kidney function in glycogen storage disease XI

JOURNAL ARTICLE published November 2023 in Science Translational Medicine

Authors: Francesco Trepiccione | Anna Iervolino | Mariavittoria D’Acierno | Sabrina Siccardi | Vincenzo Costanzo | Donato Sardella | Luigi R. De La Motte | Luciano D’Apolito | Antonio Miele | Alessandra F. Perna | Giovanna Capolongo | Miriam Zacchia | Sebastian Frische | Rikke Nielsen | Leopoldo Staiano | Irene Sambri | Rossella De Cegli | Robert Unwin | Dominique Eladari | Giovambattista Capasso

Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR -mutant lung cancer

JOURNAL ARTICLE published September 2021 in Science Translational Medicine

Authors: Pınar Özden Eser | Raymond M. Paranal | Jieun Son | Elena Ivanova | Yanan Kuang | Heidi M. Haikala | Ciric To | Jeffrey J. Okoro | Kshiti H. Dholakia | Jihyun Choi | Yoonji Eum | Atsuko Ogino | Pavlos Missios | Dalia Ercan | Man Xu | Michael J. Poitras | Stephen Wang | Kenneth Ngo | Michael Dills | Masahiko Yanagita | Timothy Lopez | Mika Lin | Jeanelle Tsai | Nicolas Floch | Emily S. Chambers | Jennifer Heng | Rana Anjum | Alison D. Santucci | Kesi Michael | Alwin G. Schuller | Darren Cross | Paul D. Smith | Geoffrey R. Oxnard | David A. Barbie | Lynette M. Sholl | Magda Bahcall | Sangeetha Palakurthi | Prafulla C. Gokhale | Cloud P. Paweletz | George Q. Daley | Pasi A. Jänne

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

JOURNAL ARTICLE published 9 October 2019 in Science Translational Medicine

Authors: Honghai Liu | Cheng-Hai Zhang | Niyatie Ammanamanchi | Sangita Suresh | Christopher Lewarchik | Krithika Rao | Gerrida M. Uys | Lu Han | Maryline Abrial | Dean Yimlamai | Balakrishnan Ganapathy | Christelle Guillermier | Nathalie Chen | Mugdha Khaladkar | Jennifer Spaethling | James H. Eberwine | Junhyong Kim | Stuart Walsh | Sangita Choudhury | Kathryn Little | Kimberly Francis | Mahesh Sharma | Melita Viegas | Abha Bais | Dennis Kostka | Jun Ding | Ziv Bar-Joseph | Yijen Wu | Vijay Yechoor | Mousumi Moulik | Jennifer Johnson | Jacqueline Weinberg | Miguel Reyes-Múgica | Matthew L. Steinhauser | Bernhard Kühn