Catering to chondrocytes

JOURNAL ARTICLE published 28 November 2018 in Science Translational Medicine

Authors: Christopher H. Evans

Arginine vasopressin in cerebrospinal fluid is a marker of sociality in nonhuman primates

JOURNAL ARTICLE published 2 May 2018 in Science Translational Medicine

Research funded by National Institutes of Health (R21HD079095) | National Institutes of Health (P51OD011107) | National Institutes of Health (R24OD010962) | Simons Foundation (274472) | Simons Foundation (342873)

Authors: Karen J. Parker | Joseph P. Garner | Ozge Oztan | Erna R. Tarara | Jiang Li | Valentina Sclafani | Laura A. Del Rosso | Katie Chun | Sean W. Berquist | Michael G. Chez | Sonia Partap | Antonio Y. Hardan | Elliott H. Sherr | John P. Capitanio

Preterm Cerebellar Growth Impairment After Postnatal Exposure to Glucocorticoids

JOURNAL ARTICLE published 19 October 2011 in Science Translational Medicine

Authors: Emily W. Y. Tam | Vann Chau | Donna M. Ferriero | A. James Barkovich | Kenneth J. Poskitt | Colin Studholme | Eric D.-Y. Fok | Ruth E. Grunau | David V. Glidden | Steven P. Miller

Genomics in Clinical Practice: Lessons from the Front Lines

JOURNAL ARTICLE published 17 July 2013 in Science Translational Medicine

Authors: Howard J. Jacob | Kelly Abrams | David P. Bick | Kent Brodie | David P. Dimmock | Michael Farrell | Jennifer Geurts | Jeremy Harris | Daniel Helbling | Barbara J. Joers | Robert Kliegman | George Kowalski | Jozef Lazar | David A. Margolis | Paula North | Jill Northup | Altheia Roquemore-Goins | Gunter Scharer | Mary Shimoyama | Kimberly Strong | Bradley Taylor | Shirng-Wern Tsaih | Michael R. Tschannen | Regan L. Veith | Jaime Wendt-Andrae | Brandon Wilk | Elizabeth A. Worthey

From passengers to co-pilots: Patient roles expand

JOURNAL ARTICLE published 10 June 2015 in Science Translational Medicine

Authors: Margaret Anderson | K. Kimberly McCleary

T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway

JOURNAL ARTICLE published 7 May 2014 in Science Translational Medicine

Authors: Aline Bozec | Mario M. Zaiss | Rosebeth Kagwiria | Reinhard Voll | Manfred Rauh | Zhu Chen | Sandra Mueller-Schmucker | Richard A. Kroczek | Lucie Heinzerling | Muriel Moser | Andrew L. Mellor | Jean-Pierre David | Georg Schett

Durable sequence stability and bone marrow tropism in a macaque model of human pegivirus infection

JOURNAL ARTICLE published 16 September 2015 in Science Translational Medicine

Research funded by NIH (TW009237,R01 AI077376,R01 AI084787) | National Institute of General Medical Sciences (T32GM081061) | Office of Research Infrastructure Programs (P51 RR000167) | Research Facilities Improvement Program (RR15459-01,RR020141-01) | University of Wisconsin's Medical Scientist Training Program (T32 GM008692) | National Research Service Award (T32 AI55397)

Authors: Adam L. Bailey | Michael Lauck | Mariel Mohns | Eric J. Peterson | Kerry Beheler | Kevin G. Brunner | Kristin Crosno | Andres Mejia | James Mutschler | Matthew Gehrke | Justin Greene | Adam J. Ericsen | Andrea Weiler | Gabrielle Lehrer-Brey | Thomas C. Friedrich | Samuel D. Sibley | Esper G. Kallas | Saverio Capuano | Jeffrey Rogers | Tony L. Goldberg | Heather A. Simmons | David H. O’Connor

Tadalafil Alleviates Muscle Ischemia in Patients with Becker Muscular Dystrophy

JOURNAL ARTICLE published 28 November 2012 in Science Translational Medicine

Authors: Elizabeth A. Martin | Rita Barresi | Barry J. Byrne | Evgeny I. Tsimerinov | Bryan L. Scott | Ashley E. Walker | Swaminatha V. Gurudevan | Francine Anene | Robert M. Elashoff | Gail D. Thomas | Ronald G. Victor

Cyclin-dependent–like kinase 5 is required for pain signaling in human sensory neurons and mouse models

JOURNAL ARTICLE published 8 July 2020 in Science Translational Medicine

Authors: Paolo La Montanara | Arnau Hervera | Lucas L. Baltussen | Thomas H. Hutson | Ilaria Palmisano | Francesco De Virgiliis | Guiping Kong | Jessica Chadwick | Yunan Gao | Katalin Bartus | Qasim A. Majid | Nikos Gorgoraptis | Kingsley Wong | Jenny Downs | Tommaso Pizzorusso | Sila K. Ultanir | Helen Leonard | Hongwei Yu | David S. Millar | Nagy Istvan | Nicholas D. Mazarakis | Simone Di Giovanni

Immunity elicited by natural infection or Ad26.COV2.S vaccination protects hamsters against SARS-CoV-2 variants of concern

JOURNAL ARTICLE published 3 November 2021 in Science Translational Medicine

Authors: Lisa H. Tostanoski | Jingyou Yu | Noe B. Mercado | Katherine McMahan | Catherine Jacob-Dolan | Amanda J. Martinot | Cesar Piedra-Mora | Tochi Anioke | Aiquan Chang | Victoria M. Giffin | David L. Hope | Huahua Wan | Esther A. Bondzie | Shant H. Mahrokhian | Linda M. Wrijil | Katherine Bauer | Laurent Pessaint | Maciel Porto | Joseph Piegols | Andrew Faudree | Brittany Spence | Swagata Kar | Fatima Amanat | Florian Krammer | Hanne Andersen | Mark G. Lewis | Frank Wegmann | Roland Zahn | Hanneke Schuitemaker | Dan H. Barouch

The gut microbiota posttranslationally modifies IgA1 in autoimmune glomerulonephritis

JOURNAL ARTICLE published 27 March 2024 in Science Translational Medicine

Authors: Patrick J. Gleeson | Nicolas Benech | Jonathan Chemouny | Eleftheria Metallinou | Laureline Berthelot | Jennifer da Silva | Julie Bex-Coudrat | Erwan Boedec | Fanny Canesi | Carine Bounaix | Willy Morelle | Maryse Moya-Nilges | John Kenny | Liam O’Mahony | Loredana Saveanu | Bertrand Arnulf | Aurélie Sannier | Eric Daugas | François Vrtovsnik | Patricia Lepage | Harry Sokol | Renato C. Monteiro

Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections

JOURNAL ARTICLE published 7 July 2021 in Science Translational Medicine

Research funded by National Institute of Allergy and Infectious Diseases (T32AI052071) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR073665) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR069502)

Authors: Martin P. Alphonse | Jessica H. Rubens | Roger V. Ortines | Nicholas A. Orlando | Aman M. Patel | Dustin Dikeman | Yu Wang | Ivan Vuong | Daniel P. Joyce | Jeffrey Zhang | Mohammed Mumtaz | Haiyun Liu | Qi Liu | Christine Youn | Garrett J. Patrick | Advaitaa Ravipati | Robert J. Miller | Nathan K. Archer | Lloyd S. Miller

A phase 2 clinical trial of a vasopressin V1a receptor antagonist shows improved adaptive behaviors in men with autism spectrum disorder

JOURNAL ARTICLE published 8 May 2019 in Science Translational Medicine

Authors: Federico Bolognani | Marta del Valle Rubido | Lisa Squassante | Christoph Wandel | Michael Derks | Lorraine Murtagh | Jeff Sevigny | Omar Khwaja | Daniel Umbricht | Paulo Fontoura

TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci

JOURNAL ARTICLE published 9 March 2016 in Science Translational Medicine

Authors: Sang Ho Lee | Hao Wang | Marc Labroli | Sandra Koseoglu | Paul Zuck | Todd Mayhood | Charles Gill | Paul Mann | Xinwei Sher | Sookhee Ha | Shu-Wei Yang | Mihir Mandal | Christine Yang | Lianzhu Liang | Zheng Tan | Paul Tawa | Yan Hou | Reshma Kuvelkar | Kristine DeVito | Xiujuan Wen | Jing Xiao | Michelle Batchlett | Carl J. Balibar | Jenny Liu | Jianying Xiao | Nicholas Murgolo | Charles G. Garlisi | Payal R. Sheth | Amy Flattery | Jing Su | Christopher Tan | Terry Roemer

Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles

JOURNAL ARTICLE published 10 June 2020 in Science Translational Medicine

Research funded by European Commission (n°115300 and n°777394) | Bundesministerium für Bildung und Forschung (01EK1611C) | Comitato Telethon Fondazione Onlus (GGP16131)

Authors: Anne-Kathrin Lutz | Stefanie Pfaender | Berra Incearap | Valentin Ioannidis | Ilaria Ottonelli | Karl J. Föhr | Judith Cammerer | Marvin Zoller | Julia Higelin | Federica Giona | Maximilian Stetter | Nicole Stoecker | Najwa Ouali Alami | Michael Schön | Michael Orth | Stefan Liebau | Gotthold Barbi | Andreas M. Grabrucker | Richard Delorme | Michael Fauler | Benjamin Mayer | Sarah Jesse | Francesco Roselli | Albert C. Ludolph | Thomas Bourgeron | Chiara Verpelli | Maria Demestre | Tobias M. Boeckers

Sustained fetal hemoglobin induction in vivo is achieved by BCL11A interference and coexpressed truncated erythropoietin receptor

JOURNAL ARTICLE published 28 April 2021 in Science Translational Medicine

Authors: Naoya Uchida | Francesca Ferrara | Claire M. Drysdale | Morgan Yapundich | Jackson Gamer | Tina Nassehi | Julia DiNicola | Yoshitaka Shibata | Matthew Wielgosz | Yoon-Sang Kim | Matthew Bauler | Robert E. Throm | Juan J. Haro-Mora | Selami Demirci | Aylin C. Bonifacino | Allen E. Krouse | N. Seth Linde | Robert E. Donahue | Byoung Ryu | John F. Tisdale

Combination bezafibrate and nivolumab treatment of patients with advanced non–small cell lung cancer

JOURNAL ARTICLE published 14 December 2022 in Science Translational Medicine

Authors: Kentaro Tanaka | Kenji Chamoto | Sho Saeki | Ryusuke Hatae | Yuki Ikematsu | Kazuko Sakai | Nobuhisa Ando | Kazuhiro Sonomura | Shinsuke Kojima | Masanori Taketsuna | Young Hak Kim | Hironori Yoshida | Hiroaki Ozasa | Yuichi Sakamori | Tomoko Hirano | Fumihiko Matsuda | Toyohiro Hirai | Kazuto Nishio | Takuro Sakagami | Masanori Fukushima | Yoichi Nakanishi | Tasuku Honjo | Isamu Okamoto

Interfering with HIV therapy

JOURNAL ARTICLE published 4 January 2017 in Science Translational Medicine

Authors: Amanda W. Lund

Hold your nose to get lean

JOURNAL ARTICLE published 26 July 2017 in Science Translational Medicine

Authors: Jill K. Morris

Burn injuries cast their nets in blood vessels

JOURNAL ARTICLE published 2 August 2017 in Science Translational Medicine

Authors: Benjamin Levi