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Planting molecular functions in an ecological context with Arabidopsis thaliana

JOURNAL ARTICLE published 25 March 2015 in eLife

Research funded by Deutsche Forschungsgemeinschaft (DFG) (SPP1529 ADAPTOMICS, Kr1967/10-2) | Deutsche Forschungsgemeinschaft (DFG) (SPP1529 ADAPTOMICS, Kr1967/12-1)

Authors: Ute Krämer

A gut feeling about arthritis

JOURNAL ARTICLE published 5 November 2013 in eLife

Authors: Diane Mathis

Reprogramming of cardiac phosphoproteome, proteome, and transcriptome confers resilience to chronic adenylyl cyclase-driven stress

JOURNAL ARTICLE published 22 January 2024 in eLife

Authors: Jia-Hua Qu | Khalid Chakir | Kirill V Tarasov | Daniel R Riordon | Maria Grazia Perino | Allwin Jennifa Silvester | Edward G Lakatta

Coordinated regulation of gene expression in Plasmodium female gametocytes by two transcription factors

JOURNAL ARTICLE published 22 January 2024 in eLife

Research funded by Japan Society for the Promotion of Science (23H02709) | Japan Society for the Promotion of Science (21K06986) | Japan Society for the Promotion of Science (23K06515) | Japan Society for the Promotion of Science (17H01542)

Authors: Yuho Murata | Tsubasa Nishi | Izumi Kaneko | Shiroh Iwanaga | Masao Yuda

Structural mechanisms for VMAT2 inhibition by tetrabenazine

JOURNAL ARTICLE published 22 March 2024 in eLife

Research funded by National Institute of Neurological Disorders and Stroke (1R01NS134558) | National Institute of General Medical Sciences (1R01GM139297)

Authors: Michael P Dalton | Mary Hongying Cheng | Ivet Bahar | Jonathan A Coleman

Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

JOURNAL ARTICLE published 22 March 2024 in eLife

Research funded by HORIZON EUROPE European Research Council (ERC-CoG 864180) | AMMODO Science Award (2019) | National Institutes of Health (AI132359)

Authors: Chiara Andolina | Wouter Graumans | Moussa Guelbeogo | Geert-Jan van Gemert | Jordache Ramijth | Soré Harouna | Zongo Soumanaba | Rianne Stoter | Marga Vegte-Bolmer | Martina Pangos | Photini Sinnis | Katharine Collins | Sarah G Staedke | Alfred B Tiono | Chris Drakeley | Kjerstin Lanke | Teun Bousema

Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model

JOURNAL ARTICLE published 18 March 2024 in eLife

Research funded by KU Leuven (C24/17/061) | Marie-Marguerite Delacroix Foundation (Doctoral Fellowship)

Authors: Sergi Llambrich | Birger Tielemans | Ellen Saliën | Marta Atzori | Kaat Wouters | Vicky Van Bulck | Mark Platt | Laure Vanherp | Nuria Gallego Fernandez | Laura Grau de la Fuente | Harish Poptani | Lieve Verlinden | Uwe Himmelreich | Anca Croitor | Catia Attanasio | Zsuzsanna Callaerts-Vegh | Willy Gsell | Neus Martínez-Abadías | Greetje Vande Velde

Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation

JOURNAL ARTICLE published 18 March 2024 in eLife

Research funded by National Institutes of Health (R35GM139636) | National Cancer Institute (U54AI170792) | Deutsche Forschungsgemeinschaft (GZ: TR 1668/1-1) | National Institutes of Health (1F30CA247147)

Authors: Raphael Trenker | Devan Diwanji | Tanner Bingham | Kliment A Verba | Natalia Jura

Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model

JOURNAL ARTICLE published 18 March 2024 in eLife

Research funded by KU Leuven (C24/17/061) | Marie-Marguerite Delacroix Foundation (Doctoral Fellowship)

Authors: Sergi Llambrich | Birger Tielemans | Ellen Saliën | Marta Atzori | Kaat Wouters | Vicky Van Bulck | Mark Platt | Laure Vanherp | Nuria Gallego Fernandez | Laura Grau de la Fuente | Harish Poptani | Lieve Verlinden | Uwe Himmelreich | Anca Croitor | Catia Attanasio | Zsuzsanna Callaerts-Vegh | Willy Gsell | Neus Martínez-Abadías | Greetje Vande Velde

Habitat loss weakens the positive relationship between grassland plant richness and above-ground biomass

JOURNAL ARTICLE published 18 March 2024 in eLife

Research funded by National Natural Science Foundation of China (32071582) | Inner Mongolia Autonomous Region Science and Technology Plan Project (2021GG0392) | Inner Mongolia Autonomous Region Natural Science Foundation (2023ZD24)

Authors: Yongzhi Yan | Scott Jarvie | Qing Zhang

Sensitive remote homology search by local alignment of small positional embeddings from protein language models

JOURNAL ARTICLE published 15 March 2024 in eLife

Authors: Sean R Johnson | Meghana Peshwa | Zhiyi Sun

WRNIP1 prevents transcription-associated genomic instability

JOURNAL ARTICLE published 15 March 2024 in eLife

Research funded by Fondazione AIRC per la ricerca sul cancro ETS (Investigator grant 19971) | Fondazione AIRC per la ricerca sul cancro ETS (Investigator grant 17383)

Authors: Pasquale Valenzisi | Veronica Marabitti | Pietro Pichierri | Annapaola Franchitto

WRNIP1 prevents transcription-associated genomic instability

JOURNAL ARTICLE published 15 March 2024 in eLife

Research funded by Fondazione AIRC per la ricerca sul cancro ETS (Investigator grant 19971) | Fondazione AIRC per la ricerca sul cancro ETS (Investigator grant 17383)

Authors: Pasquale Valenzisi | Veronica Marabitti | Pietro Pichierri | Annapaola Franchitto

Mitochondrial genomes of Pleistocene megafauna retrieved from recent sediment layers of two Siberian lakes

JOURNAL ARTICLE published 15 March 2024 in eLife

Research funded by Deutsche Forschungsgemeinschaft (EP-98/3-1) | Biodiversa+ (BiodivScen ERA-Net COFUND)

Authors: Peter Andreas Seeber | Laura Batke | Yury Dvornikov | Alexandra Schmidt | Yi Wang | Kathleen Stoof-Leichsenring | Katie Moon | Samuel H Vohr | Beth Shapiro | Laura S Epp

Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation

JOURNAL ARTICLE published 14 July 2015 in eLife

Research funded by National Institute of Diabetes and Digestive and Kidney Diseases (R01 DK089113) | Cancer Prevention and Research Institute of Texas (Individual Investigator Award, RP130145) | U.S. Department of Defense (BCRP Idea Award W81XWH-13-1-0318) | March of Dimes Foundation (Research Grant, #6-FY13-137) | Welch Foundation (Research Grant, I-1751)

Authors: Xiaoxiao Li | Wei Wei | HoangDinh Huynh | Hao Zuo | Xueqian Wang | Yihong Wan

Immunomodulatory drug discovery from herbal medicines: Insights from organ-specific activity and xenobiotic defenses

JOURNAL ARTICLE published 15 November 2021 in eLife

Research funded by National Institutes of Health (GM131753)

Authors: Jue Shi | Jui-Hsia Weng | Timothy J Mitchison

Multivalency regulates activity in an intrinsically disordered transcription factor

JOURNAL ARTICLE published 3 August 2018 in eLife

Authors: Sarah Clark | Janette B Myers | Ashleigh King | Radovan Fiala | Jiri Novacek | Grant Pearce | Jörg Heierhorst | Steve L Reichow | Elisar J Barbar

High-resolution kinetics of herbivore-induced plant volatile transfer reveal clocked response patterns in neighboring plants

JOURNAL ARTICLE published 22 February 2024 in eLife

Research funded by Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (210651) | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (200355) | Staatssekretariat für Bildung, Forschung und Innovation (Project CANWAS) | HORIZON EUROPE Marie Sklodowska-Curie Actions (886651)

Authors: Jamie Mitchel Waterman | Tristan Michael Cofer | Lei Wang | Gaetan Glauser | Matthias Erb

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

JOURNAL ARTICLE published 23 February 2024 in eLife

Research funded by National Institute of Health (R35GM141886)

Authors: Chhavi Sood | Md Ausrafuggaman Nahid | Kendall R Branham | Matt Pahl | Susan E Doyle | Sarah E Siegrist

Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

JOURNAL ARTICLE published 22 February 2024 in eLife

Authors: Simon Desiderio | Frederick Schwaller | Kevin Tartour | Kiran Padmanabhan | Gary R Lewin | Patrick Carroll | Frederic Marmigere