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Identification of isobenzofuranone derivatives as promising antidiabetic agents: Synthesis, in vitro and in vivo inhibition of α-glucosidase and α-amylase, computational docking analysis and molecular dynamics simulations

JOURNAL ARTICLE published February 2024 in International Journal of Biological Macromolecules

Authors: Shabab Zahra | Sumera Zaib | Imtiaz Khan

In vitro α-amylase and α-glucosidase inhibitory assay v1

POSTED CONTENT published

Authors: Maira Rubí Segura-Campos

Cholinesterase, α-Glucosidase, α-Amylase, and Tyrosinase Inhibitory Effects and Antioxidant Activity of Veronica officinalis Extracts

JOURNAL ARTICLE published 31 October 2018 in Türkiye Tarımsal Araştırmalar Dergisi

Authors: Nuraniye ERUYGUR | Esra UÇAR

Meldrum-Based1H1,2,3-Triazoles as Antidiabetic Agents: Synthesis, In Vitro Glucosidase Inhibition Activity, Molecular Docking Studies, and In Silico Approach

COMPONENT published

Novel α-amylase and α-glucosidase inhibitors from selected Nigerian antidiabetic plants: anin silicoapproach

JOURNAL ARTICLE published 22 September 2022 in Journal of Biomolecular Structure and Dynamics

Authors: Ruth M. Ogboye | Rajesh B. Patil | Samson O. Famuyiwa | Kolade O. Faloye

Effect Of Fruit And Cork Extract Of Ficus Lacor Buch Ham On α/β -Glucosidase, α -Amylase, Lipase, Glucose Absorption And Uptake

JOURNAL ARTICLE published 11 July 2022 in International Journal of Life Science and Pharma Research

TLC-MS Bioautography-Based Identification of Free-Radical Scavenging, α-Amylase, and α-Glucosidase Inhibitor Compounds of Antidiabetic Tablet BGR-34

JOURNAL ARTICLE published 24 November 2020 in ACS Omega

Authors: Sultan Zahiruddin | Bushra Parveen | Mohammad Ibrahim | Ikshit Sharma | Sanchit Sharma | Anil Kumar Sharma | Rabea Parveen | Sayeed Ahmad

Review for "Brown sugar polyphenols as natural inhibitors of α‐amylase and α‐glucosidase enzymes"

PEER REVIEW published 2 May 2023

Synthesis, Glucosidase Inhibition, and In Silico Modeling Analysis of Highly Fluorinated 2Imino-1,3-thiazolines in Search of Potent Antidiabetic Agents

COMPONENT published

Antidiabetic and Hypoglycaemic Activities of Commonly Used African Traditional Vegetables

JOURNAL ARTICLE published 30 June 2023 in Pharmacognosy Journal

Authors: Nolitha Nkobole | Lavhelesani R. Managa | Gerhard Prinsloo

Antidiabetic Potential of Novel 1,3,5-Trisubstituted-2-Thioxoimidazloidin-4-One Analogues: Insights into α-Glucosidase, α-Amylase, and Antioxidant Activities

JOURNAL ARTICLE published 17 December 2022 in Pharmaceuticals

Research funded by Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia (PNURSP2022R165)

Authors: Salma M. Khirallah | Heba M. M. Ramadan | Hossam Aladl Aladl Aladl | Najla O. Ayaz | Lina A. F. Kurdi | Mariusz Jaremko | Samar Zuhair Alshawwa | Essa M. Saied

In vitro (?-Glucosidase and ?-Amylase Inhibition) and in vivo Antidiabetic Property of Phytic Acid (IP6) in Streptozotocin-Nicotinamide-Induced Type 2 Diabetes Mellitus (NIDDM) in Rats

JOURNAL ARTICLE published 15 February 2011 in Journal of Complementary and Integrative Medicine

Authors: Asokkumar Kuppusamy | Umamaheswari Muthusamy | Sivashanmugam Andichetiar Thirumalaisamy | Subhadradevi Varadharajan | Kalyanasubramaniam Ramasamy | Sambathkumar Ramanathan

Antidiabetic constituents of Dendrobium officinale as determined by high-resolution profiling of radical scavenging and α-glucosidase and α-amylase inhibition combined with HPLC-PDA-HRMS-SPE-NMR analysis

JOURNAL ARTICLE published June 2019 in Phytochemistry Letters

Research funded by Chinese Scholarship Council (201508530232) | Zhejiang University of Technology, the National Natural Science Foundation of China (81503219)

Authors: Chu Chu | Tuo Li | Hans Albert Pedersen | Kenneth T. Kongstad | Jizhong Yan | Dan Staerk

Inhibitory Effects of Four Solvent Fractions of Alnus firma on α-Amylase and α-Glucosidase.

JOURNAL ARTICLE published 30 July 2008 in Journal of Life Science

Authors: Hye-Jung Choi | Yong-Kee Jeong | Dae-Ook Kang | Woo-Hong Joo

A Two QSAR Way for Antidiabetic Agents Targeting Using α-Amylase and α-Glucosidase Inhibitors: Model Parameters Settings in Artificial Intelligence Techniques

JOURNAL ARTICLE published 20 July 2017 in Letters in Drug Design & Discovery

Authors: Karel Dieguez-Santana | Hai Pham-The | Oscar M. Rivera-Borroto | Amilkar Puris | Huong Le-Thi-Thu | Gerardo M. Casanola-Martin

Antidiabetic Activity and Phytochemical Screening of Extracts from Indonesian Plants by Inhibition of Alpha Amylase, Alpha Glucosidase and Dipeptidyl Peptidase IV

JOURNAL ARTICLE published 1 August 2015 in Pakistan Journal of Biological Sciences

Authors: Berna Elya | Rosita Handayani | Rani Sauriasari | Azizahwati . | Uqie Shabrina Hasyyati | Idam Titis Permana | Yunita Indah Permatasar

An insight into antidiabetic properties of six medicinal and edible mushrooms: Inhibition of α-amylase and α-glucosidase linked to type-2 diabetes

JOURNAL ARTICLE published January 2019 in South African Journal of Botany

Research funded by Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja (173032)

Authors: D. Stojkovic | M. Smiljkovic | A. Ciric | J. Glamoclija | L. Van Griensven | I.C.F.R. Ferreira | M. Sokovic

Nineteen New FlavanolFatty Alcohol Hybrids with Glucosidase and PTP1B Dual Inhibition: One Unusual Type of Antidiabetic Constituent from Amomum tsao-ko

COMPONENT published

Machine Learning-Based Amino Acid Substitution of Short Peptides: Acquisition of Peptides with Enhanced Inhibitory Activities against Amylase and Glucosidase

COMPONENT published

Decision letter for "Brown sugar polyphenols as natural inhibitors of α‐amylase and α‐glucosidase enzymes"

PEER REVIEW published 6 June 2023